DeepMind的游戏理论与多代理团队研究多学科学习的几个方面，从计算近似值到游戏理论中的基本概念，再到在富裕的空间环境中模拟社会困境，并在困难的团队协调任务中培训3-D类人动物。我们小组的一个签名目的是使用DeepMind在DeepMind中提供的资源和专业知识，以深入强化学习来探索复杂环境中的多代理系统，并使用这些基准来提高我们的理解。在这里，我们总结了我们团队的最新工作，并提出了一种分类法，我们认为这重点介绍了多代理研究中许多重要的开放挑战。

Interaction and cooperation with humans are overarching aspirations of artificial intelligence (AI) research. Recent studies demonstrate that AI agents trained with deep reinforcement learning are capable of collaborating with humans. These studies primarily evaluate human compatibility through "objective" metrics such as task performance, obscuring potential variation in the levels of trust and subjective preference that different agents garner. To better understand the factors shaping subjective preferences in human-agent cooperation, we train deep reinforcement learning agents in Coins, a two-player social dilemma. We recruit participants for a human-agent cooperation study and measure their impressions of the agents they encounter. Participants' perceptions of warmth and competence predict their stated preferences for different agents, above and beyond objective performance metrics. Drawing inspiration from social science and biology research, we subsequently implement a new "partner choice" framework to elicit revealed preferences: after playing an episode with an agent, participants are asked whether they would like to play the next round with the same agent or to play alone. As with stated preferences, social perception better predicts participants' revealed preferences than does objective performance. Given these results, we recommend human-agent interaction researchers routinely incorporate the measurement of social perception and subjective preferences into their studies.

研究多层合作研究中的一个关键挑战是不仅需要有效合作的个人代理，而且需要与谁合作。当其他代理人隐藏的情况下，可能是错误的动机和目标时，这在局势中特别关键。社交扣除游戏提供途径来研究个人如何学习如何综合有关其他人的潜在不可靠的信息，并阐明其真正的动机。在这项工作中，我们展示了隐藏的议程，这是一个双队的社交扣除游戏，为在未知团队对齐的情况下学习学习代理的2D环境。环境承认两支球队的丰富战略。在隐藏议程中培训的强化学习代理表明，代理商可以学习各种行为，包括合作和投票，而无需以自然语言沟通。

与人类合作需要迅速适应他们的个人优势，缺点和偏好。遗憾的是，大多数标准的多智能经纪增强学习技术，如自助（SP）或人口剧（PP），产生培训合作伙伴的代理商，并且对人类不完全概括。或者，研究人员可以使用行为克隆收集人体数据，培训人类模型，然后使用该模型培训“人类感知”代理（“行为克隆播放”或BCP）。虽然这种方法可以改善代理商的概括到新的人类共同球员，但它涉及首先收集大量人体数据的繁重和昂贵的步骤。在这里，我们研究如何培训与人类合作伙伴合作的代理的问题，而无需使用人类数据。我们认为这个问题的症结是制作各种培训伙伴。从竞争域中取得成功的多智能经纪人方法绘制灵感，我们发现令人惊讶的简单方法非常有效。我们培养我们的代理商合作伙伴作为对自行发行代理人口的最佳反应及其过去培训的过去检查点，这是我们呼叫虚构共同扮演（FCP）的方法。我们的实验专注于两位运动员协作烹饪模拟器，最近被提议作为与人类协调的挑战问题。我们发现，与新的代理商和人类合作伙伴配对时，FCP代理商会显着高于SP，PP和BCP。此外，人类还报告了强烈的主观偏好，以与所有基线与FCP代理合作。

We present a machine-learning framework to accurately characterize morphologies of Active Galactic Nucleus (AGN) host galaxies within $z<1$. We first use PSFGAN to decouple host galaxy light from the central point source, then we invoke the Galaxy Morphology Network (GaMorNet) to estimate whether the host galaxy is disk-dominated, bulge-dominated, or indeterminate. Using optical images from five bands of the HSC Wide Survey, we build models independently in three redshift bins: low $(0<z<0.25)$, medium $(0.25<z<0.5)$, and high $(0.5<z<1.0)$. By first training on a large number of simulated galaxies, then fine-tuning using far fewer classified real galaxies, our framework predicts the actual morphology for $\sim$ $60\%-70\%$ host galaxies from test sets, with a classification precision of $\sim$ $80\%-95\%$, depending on redshift bin. Specifically, our models achieve disk precision of $96\%/82\%/79\%$ and bulge precision of $90\%/90\%/80\%$ (for the 3 redshift bins), at thresholds corresponding to indeterminate fractions of $30\%/43\%/42\%$. The classification precision of our models has a noticeable dependency on host galaxy radius and magnitude. No strong dependency is observed on contrast ratio. Comparing classifications of real AGNs, our models agree well with traditional 2D fitting with GALFIT. The PSFGAN+GaMorNet framework does not depend on the choice of fitting functions or galaxy-related input parameters, runs orders of magnitude faster than GALFIT, and is easily generalizable via transfer learning, making it an ideal tool for studying AGN host galaxy morphology in forthcoming large imaging survey.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, well-documented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare.

Federated learning (FL) enables the building of robust and generalizable AI models by leveraging diverse datasets from multiple collaborators without centralizing the data. We created NVIDIA FLARE as an open-source software development kit (SDK) to make it easier for data scientists to use FL in their research and real-world applications. The SDK includes solutions for state-of-the-art FL algorithms and federated machine learning approaches, which facilitate building workflows for distributed learning across enterprises and enable platform developers to create a secure, privacy-preserving offering for multiparty collaboration utilizing homomorphic encryption or differential privacy. The SDK is a lightweight, flexible, and scalable Python package, and allows researchers to bring their data science workflows implemented in any training libraries (PyTorch, TensorFlow, XGBoost, or even NumPy) and apply them in real-world FL settings. This paper introduces the key design principles of FLARE and illustrates some use cases (e.g., COVID analysis) with customizable FL workflows that implement different privacy-preserving algorithms. Code is available at https://github.com/NVIDIA/NVFlare.

在全球范围内消除语言障碍的目标的驱动下，机器翻译已巩固自己是当今人工智能研究的关键重点。但是，这样的努力围绕着一小部分语言结合在一起，留下了绝大多数低资源的语言。在确保安全，高质量的结果的同时，在牢记道德考虑的同时，打破200个语言障碍需要什么？没有留下的语言，我们首先通过与母语人士的探索性访谈来解决对低资源语言翻译支持的必要性来应对这一挑战。然后，我们创建了旨在缩小低资源和高资源语言之间的性能差距的数据集和模型。更具体地说，我们开发了一种有条件的计算模型，基于专家的稀疏混合物，该模型经过针对针对低资源语言量身定制的新颖有效的数据挖掘技术培训的。我们提出了多次建筑和培训改进，以抵消数千个任务的培训。至关重要的是，我们使用人类翻译的基准，Flores-200评估了40,000多种不同的翻译方向的性能，并将人类评估与新型毒性基准相结合，涵盖Flores-200的所有语言，以评估翻译安全性。我们的模型相对于先前的最新技术，实现了44％BLEU的改善，为实现通用翻译系统奠定了重要的基础。最后，我们开源此工作中描述的所有贡献，可在https://github.com/facebookresearch/fairseq/tree/nllb上访问。

对从FFPE组织块制备的载玻片上切割的染色组织的光学显微镜检查是组织诊断的金标准。此外，任何病理学家的诊断能力和专业知识都取决于他们在常见和稀有变体形态上的直接经验。最近，深度学习方法已被用来成功显示此类任务的高度准确性。但是，获得专家级注释的图像是一项昂贵且耗时的任务，人为合成的组织学图像可能会非常有益。在这里，我们提出了一种方法，不仅可以生成组织学图像，从而重现普通疾病的诊断形态特征，而且还提供了产生新的和罕见形态的用户能力。我们的方法涉及开发一种生成的对抗网络模型，该模型综合了由类标签约束的病理图像。我们研究了该框架合成现实的前列腺和结肠组织图像的能力，并评估了这些图像在增强机器学习方法的诊断能力以及通过一组经验丰富的解剖病理学家的可用性方面的实用性。我们的框架生成的合成数据在训练深度学习模型中进行了类似于实际数据进行诊断。病理学家无法区分真实图像和合成图像，并显示出相似的前列腺癌分级的观察者间一致性。我们扩展了从结肠活检中显着复杂图像的方法，并表明也可以再现了此类组织中的复杂微环境。最后，我们介绍了用户通过简单的语义标签标记来生成深层组织学图像的能力。